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Take a trip into an upgraded, more organized inbox. Sign in and start exploring all the free, organizational tools for your email. Check out new themes, send GIFs, find every photo you’ve ever sent or received, and search your account faster than ever.. Renal dysfunction is highly prevalent in patients with heart failure. Furthermore, worsening renal function in patients with acute decompensated heart failure (ADHF), the so-called cardiorenal syndrome, impacts short and long-term morbidity and mortality. In recent years, more evidence has surfaced from clinical trials and heart failure registries that a complex cross-talk between the kidney.